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Comfort Inn

Selected Favorite

1821 N. Missouri St, Macon, MO, US, 63552-1973

  • Phone: (660) 395-8000
  • Fax: (660) 395-8001
Platinum Medal

Choice Preferred Platinum Award

Hotels that achieve the prestigious Platinum Award represent the top 3% of hotels within each Choice brand. The awards are based on a ranking system that measures guest satisfaction, product quality, room condition and cleanliness, and staff service. These properties have a proven track record of providing exceptional guest service and facilities.

Green Hotel

Supports Green Practices

"Supports Green Initiatives" designates a hotel's participation in an optional environmental program that includes the use of energy-efficient lighting, guestroom towel/linen re-use, and on-premise recycling. "Supports Green Initiatives" does not represent an official certification of any kind.

4.8 out of 5 (202 reviews)
97% of guests recommend this hotel

Points of Interest

Get Driving Directions:

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Directions to Our Hotel:

From Kansas City: I-35 North to Highway 36 East. 100 miles to Macon exit. Turn left. Hotel on left. From St Louis: I-70 West to Highway 63 North. 60 miles to Macon. North of Macon on left. From Kirksville: Highway 63 South. 35 miles to Macon. Hotel on right of Highway 63. From Hannibal: Highway 36 West. 65 miles to Macon. Exit and go north. Hotel is on west side. When using a GPS device or web map to locate the hotel, please use hotel's coordinates where possible: Latitude: 39.757435, Longitude: -92.468222. Please contact the hotel for additional directions prior to traveling.

Directions to/from a nearby airport:

Kansas City Int'l Airport (MCI)To hotel › From hotel ›
Lambert-St. Louis Int'l Arpt (STL)To hotel › From hotel ›
AMTRAK Train Station

Hotel Latitude/Longitude:

Latitude: 39.757534       Longitude: -92.468437

Use these coordinates to locate this hotel when using a GPS device or web map.


AMTRAK Train Station20.0mi/32.2km N
Lambert-St. Louis Int'l Arpt165.0mi/265.5km E
Kansas City Int'l Airport170.0mi/273.6km W
Note: Distance is displayed as straight line from the city center or point of interest. Driving distance may vary.
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