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Comfort Inn & Suites

Selected Favorite

2020 Highland Way, Mitchell, SD, US, 57301

  • Phone: (605) 990-2400
  • Fax: (605) 990-2408
4.6 out of 5 (109 reviews)
94% of guests recommend this hotel

Arts & Museums

Sioux Empire Medical Museum

1100 South Euclid Avenue
Sioux Falls, South Dakota 57104
605-333-6397
See medical advancements from the early 1900's to the present.
Earn valuable points toward free nights.