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Comfort Inn

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5100 Old Scioto Trail, Portsmouth, OH, US, 45662

  • Phone: (740) 353-3232
  • Fax: (740) 355-0415
4.4 out of 5 (156 reviews)
91% of guests recommend this hotel


Saint Mary of the Annunciation Catholic Church

524 Sixth Street
Portsmouth, OH 45662
+1 740 354 4551
The St. Mary's Catholic Church is a beautiful historic church established in 1870. Located at the intersection of 5th and Markets Streets, it is built with the Germanic Gothic Revival style of architecture. The church is in service and holds masses as per routine. It became a part of the National Register of Historic Places in 1979.
Earn valuable points toward free nights.